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Normal Adipose Tissue
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Normal Adipose Tissue

A low power view of normal adipose tissue.
The most striking feature of normal adipose tissue is the apparent lack of substance.
This is because the majority of this tissue (normal neutral fat) has been extracted during the fixation and processing of the tissue.
What remains is wispy cytoplasm of the individual adipocyte that remains behind.
The dark dots that you see in this field are the adipocyte nuclei that are embedded in the cytoplasm of the individual cells.
At the very center of this image is a blood vessel that supplies the tissue with blood.
(Description By:T.V. Rajan, M.D. )
(Image Contrib. by:T.V. Rajan, M.D. UCHC )
Normal adipose tissue
Etiology

N/A
Pathogenesis

N/A,
Epidemiology

N/A
General Gross Description

Normal adipose tissue is grossly lobulated and yellowish in color.
General Microscopic Description

Microscopically, it is composed of typical polygonal cells that can range up to 120 microns in diameter.
The entire volume of the cell is usually taken up by a single large droplet of lipid.
This droplet of lipid is surrounded by a thin rim of eosinophilic staining cytoplasm.
The overall microscopic appearance is of a thin, lacy network of cytoplasm, separated by large polygonal, empty spaces.
Adipocyte nuclei are dark staining and highly compressed.
Fat is supplied by relatively abundant blood vessels that course between the adipocytes in the corners made by adjacent cells.
Clinical Correlation

N/A
References
Bloom and Fawcett: A textbook of Histology. 12th Edition. Chapman & Hall. 1994. pp 170
Normal adipose tissue
Synopsis by: T.V.Rajan, M.D., Ph.D. (T1X010M00100)[586]
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