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Synovial Hyperplasia
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Synovial Hyperplasia

Normal synovium consists of a barely visible layer of simple squamous cells closely applied to the joint capsule.
In this image, however, notice the prominent finger-like projections of hyperplastic synovial cells, which surround a central fibral vascular core.
(Description By:T.V. Rajan, M.D. )
(Image Contrib. by:T.V. Rajan, M.D. UCHC )
Synovial Hyperplasia
Etiology

Associated with any irritant within the joint (torn cartilage, chipped bone).
Associated with inflammatory process including such disorders as rheumatoid arthritis.
Pathogenesis

Epithelial hyperplasia in response to injury.
Inflammation or mechanical trauma may cause the injury.,
Epidemiology

Frequent.
Epidemiology that of injury to joints and of arthritic diseases.
General Gross Description

Congested, thickened, granular synovium.
General Microscopic Description

Multiple layers of synovium.
May be associated with inflammation, foreign material, hemorrhage, and/or scar.
Clinical Correlation

Non specific finding associated with injury.
References

Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1250-9.
Synovial Hyperplasia
Synopsis by: Melinda Sanders M.D. (T12040M72000)[614]
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