• Normal synovium consists of a barely visible layer of
simple squamous cells closely applied to the joint capsule.
• In this image, however, notice the prominent finger-like projections of hyperplastic synovial cells, which surround a central fibral vascular core.
• Associated with any irritant within the joint (torn cartilage, chipped bone).
• Associated with inflammatory process including such disorders as rheumatoid arthritis.
• Epithelial hyperplasia in response to injury.
• Inflammation or mechanical trauma may cause the injury.
• Epidemiology that of injury to joints and of arthritic diseases.
• Non specific finding associated with injury.
|General Gross Description|
• Congested, thickened, granular synovium.
|General Micro Description|
• Multiple layers of synovium.
• May be associated with inflammation, foreign material, hemorrhage, and/or scar.
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1250-9.