• High power view of a papillary-like growth of synovium
in a case of synovial hyperplasia.
• This image clearly demonstrates the central
fibrovascular core of the papillary projections.
• The four space-like lesions containing red blood cells
are vascular channels.
• The pink whorled material represents the collagen and
the elongated nuclei within this red swirling material
are fibroblast nuclei.
• To the left of this image are the deeply staining columnar to cuboidal cells that represent the synovial epithelium.
• Associated with any irritant within the joint (torn cartilage, chipped bone).
• Associated with inflammatory process including such disorders as rheumatoid arthritis.
• Epithelial hyperplasia in response to injury.
• Inflammation or mechanical trauma may cause the injury.
• Epidemiology that of injury to joints and of arthritic diseases.
• Non specific finding associated with injury.
|General Gross Description|
• Congested, thickened, granular synovium.
|General Micro Description|
• Multiple layers of synovium.
• May be associated with inflammation, foreign material, hemorrhage, and/or scar.
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1250-9.