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High power view of normal adipose tissue - for comparison with a liposarcoma
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High power view of normal adipose tissue - for comparison with a liposarcoma

A high power view of normal adipocytes.
The green arrows encircle a typical normal adipocyte.
Much of the cell is composed of a single large globule of fat that is extracted during the fixation, embedding, sectioning and staining procedures, leaving behind a thin rim of cytoplasm.
This rim of cytoplasm stains eosinophilic and lie at the tips of the green pointers.
The typical adipocyte nucleus is condensed and lies embedded within this rim of cytoplasm.
Two typical adipocyte nuclei are indicated by the two black arrows.
(Description By:T.V.Rajan, M.D. )
(Image Contrib. by:T.V.Rajan, M.D. UCHC )
Normal adipose tissue
Etiology

N/A
Pathogenesis

N/A,
Epidemiology

N/A
General Gross Description

Normal adipose tissue is grossly lobulated and yellowish in color.
General Microscopic Description

Microscopically, it is composed of typical polygonal cells that can range up to 120 microns in diameter.
The entire volume of the cell is usually taken up by a single large droplet of lipid.
This droplet of lipid is surrounded by a thin rim of eosinophilic staining cytoplasm.
The overall microscopic appearance is of a thin, lacy network of cytoplasm, separated by large polygonal, empty spaces.
Adipocyte nuclei are dark staining and highly compressed.
Fat is supplied by relatively abundant blood vessels that course between the adipocytes in the corners made by adjacent cells.
Clinical Correlation

N/A
References
Bloom and Fawcett: A textbook of Histology. 12th Edition. Chapman & Hall. 1994. pp 170
Normal adipose tissue
Synopsis by: T.V.Rajan, M.D., Ph.D. (T1X010M00100)[586]
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