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Intraductal Papilloma of Breast (10X)
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Intraductal Papilloma of Breast (10X)

This low power view demonstrates an intracystic proliferation.
There is a proliferation of finger-like processes into the lumen.
The fingers contain a fibrovascular stroma.
The lining epithelium contains duct epithelium and myoepithelial cells.
(Description By:Faripour Forouhar, M.D. )
(Image Contrib. by:Faripour Forouhar, M.D. UCHC )
Intraductal Papilloma
Etiology

Unknown
Pathogenesis

Unknown.,
Epidemiology

Responsible for up to 1/2 of abnormal nipple discharge
General Gross Description

Usually in major nipple duct, close to nipple
Usually < 1 cm. in size
General Microscopic Description

Multiple papillae with fibrovascular cores
Cells overlying papillae resemble normal duct epithelial cells
Myoepithelial cells also present
Clinical Correlation

Bloody nipple discharge or small subareolar mass
Will recur if duct system not excised
References

Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, p. 1099
Intraductal Papilloma
Synopsis by: Melinda Sanders M.D. (T04000M85030)[324]
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