Tay Sachs Disease
Tay Sachs Disease

High power view of anterior horn cell neurons excess lipid,due to the storage disorder.
On electron microscopy, this stored material is made of concentrically laminated bodies.
The lipid accumulates in neurons, interfering with the function of organelles and finally leading to the death of the neuron.
(Description By:Margaret Grunnet, M.D. )
(Image Contrib. by:Margaret Grunnet, M.D. UCHC )