Lissencephaly
Lissencephaly

This is a horizontal section of a microcephalic brain which shows areas with no convolutions--lissencephaly or smooth brain and areas of large gyri--pachygyria.
Note how thick the cortex is and how thin the white matter, characteristic of lissencephaly and pachygria.
(Description By:Margaret Grunnet, M.D. )
(Image Contrib. by:Margaret Grunnet, M.D. UCHC )