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| Normal Aortic Valve |
| Etiology N.A. |
| Pathogenesis N.A., |
| Epidemiology N.A. |
| General Gross Description Three semilunar pocket-like valvules called cusps, and named right, left, and posterior cusps. Each cusp is attached by its semicircular border to the aortic valve ring. The cusps are mutually attached laterally where the free margins are attached to the valve ring. These junctions are called the commissures. The middle of the free edge of each cusp is thickened to form a nodule, on each side of which along the free edge is a thin narrow crescentic area called a lunule. The endothelium on the superior surface is continuous with that of the aorta, and the lining of the inferior surface is continuous with endocardium. The cusps are thin and translucent. |
| General Microscopic Description There are 3 distinct layers, namely fibrosa, ventricularis, and spongiosa lined externally by an endothelium throughout. The fibrosa is a distinct layer of dense collagenous fibrous tissue subjacent to the endothelium of the superior or aortic surface. The ventricularis is a distinct layer of elastic tissue subjacent to the endothelium of the inferior or ventricular surface. The spongiosa is a thin layer of loose mesenchymal tissue between the other two. |
| Clinical Correlation N.A. |
| References Histology for Pathologists. Sternberg SS ed. New York: Raven Press, 1992. pp. 222-223. |
| Normal Aortic Valve |
| Synopsis by: J. Hasson, MD (T39000M00100)[601] |
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