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| Parathyroid Adenoma |
| Etiology • unknown |
| Pathogenesis • unknown • secretes unregulated parathormone resulting in elevation of serum calcium by renal retention, GI absorption and bone mobilization, |
| Epidemiology • 25/100,000 in US • 3:1 female predominance • age > 50 |
| General Gross Description • Single • Red-tan • Occasionally can see compressed rim of normal parathyroid |
| General Microscopic Description • Composed of any cell types within parathyroid • No stromal or intracellular fat • May see compressed rim of normal parathyroid • Nuclear atypia and mitoses are NOT indicative of malignancy |
| Clinical Correlation • usually detected in asymptomatic patient • rarely see evidence of osteitis fibrosa cystica (due to osteoclast activity and bone resorption) and renal stones |
| References • Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1144-146 |
| Parathyroid Adenoma |
| Synopsis by: Melinda Sanders m.D. (T97000M81400)[148] |
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