Squamous Cell Carcinoma-in-situ x40
Squamous Cell Carcinoma-in-situ x40

Nuclei are enlarged with marked variation in nuclear size and shape
The nuclear/cytoplasmic ratio is markedly increased
Abnormal mitotic figures are seen(arrow)
Note the architectural disarray with a loss of the orderly epithelial layering seen in normal tissue
(Description By:Martin Nadel, M.D. )
(Image Contrib. by:Martin Nadel, M.D. UCHC )