Cytomegalovirus x40
Cytomegalovirus x40

Classic CMV intranuclear inclusions are deep purple, occupy >50% of the nuclear diameter, have a clear perinuclear zone and a rim of condensed nuclear chromatin
In this case the perinuclear clear zone is obliterated by the large size of the CMV inclusion
Intracytoplasmic CMV inclusions can be present as small punctate dots(nicely seen in this case)
(Description By:Martin Nadel, M.D. )
(Image Contrib. by:Martin Nadel, M.D. UCHC )