| • The mucosa and lumen of the appendix have been replaced
by fibrofatty tissue
• Portions of the muscularis show fibrous replacement confirming the post inflammatory reparative
nature of the lesion
• There is no evidence of necrosis or acute inflammation
• The original mucosa and lumen can be defined by following muscularis propria (arrow) in its circular course |
| Healed Appendicitis |
| Etiology |
•See acute appendicitis |
| Pathogenesis |
•See acute appendicitis |
| Epidemiology |
•See acute appendicitis |
| Clinical |
•Healed appendicitis is rarely found, usually in an appendix incidentally
removed •A previous history of abdominal pain or symptoms consistent with
undiagnosed acute appendicitis can often be elicited |
| General Gross Description |
•This uncommon
lesion commonly resembles a normal appendix on external examination •The lumen shows fibrous obliteration •Some cases with marked fibrosis show mild widening of the appendix with an
increased grey white appearance to the serosa |
| General Micro Description |
•Partial fibrous replacement of the muscularis propria with or without
some resolving chronic inflammation is required for the diagnosis as well as fibrous or fibrofatty obliteration of the lumen •Fibrofatty obliteration of the lumen alone is not considered to represent
healed appendicitis and its cause is unknown |
| Reference |
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 823-824
|