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| Normal Jejunum |
| Etiology • Not applicable. |
| Pathogenesis • Not applicable., |
| Epidemiology • Not applicable. |
| General Gross Description • Begins at Ligament of Treitz and arbitrarily includes proximal 40% of remaining small intestine • Thicker wall and greater diameter proximally • More prominent plicae in jejunum; less fatty mesentery • Supplied by superior mesenteric artery |
| General Microscopic Description • Mucosa thrown up in plicae and arranged in villi to maximize absorptive area • Villi project above surface; crypts of Lieberkuhn extend between the villi to the muscularis mucosa • Villi lined by absorptive tall columnar cells and goblet cells • One intraepithelial T lymphocyte/5 glandular cells • Scattered endocrine cells • Crypts contain stem cells, endocrine cells, and Paneth cells with supranuclear, eosinophilic granules • Plasma cells, lymphocytes, mast cells, eosinophils, and histiocytes normal in lamina propria • Submucosa beneath the muscularis mucosa, contains Meissner's plexus of ganglion cells and nerves • Muscularis propria with inner circular and outer longitudinal layers separated by Auerbach's plexus • Outer surface covered by visceral peritoneum |
| Clinical Correlation • Not applicable. |
| References • Histology for Pathologists. Sternberg SS ed. New York: Raven Press, 1992. pp. 547-563. |
| Normal Jejunum |
| Synopsis by: Melinda Sanders M.D. (T64000M00100)[540] |
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