Cirrhosis

Cirrhosis •A high power view of a cirrhotic liver, to demonstrate some of the details of the architecture. •In a normal liver, one would see lobules composed mostly of hepatocytes, with a central vein and flanked by portal tracts, with very little connective tissue between the lobules. •In this image, one sees two regenerating nodules of liver cells, with no central vein and no portal tracts. •They are separated from each other by abundant connective tissue (the pink staining, fibrous material), which contains chronic inflammatory cells. (Description By:T.V.Rajan, M.D. ) (Image Contrib. by:T.V.Rajan, M.D. UCHC )