| Lymphoma
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Etiology
•Unknown
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Pathogenesis
•Unknown,
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Epidemiology
•Involvement of the liver in systemic lymphomas occurs
in approximately 50% of all cases.
•Any form of lymphoma (Hodgkins or non-Hodgkins
Disease) can involve the liver.
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General Gross Description
•Grossly, the liver shows some evidence of involvement
depending upon the extent of tumor.
•Occasionally, nodular deposits may be seen.
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General Microscopic Description
•Microscopically, the lymphoma looks like that seen in lymph nodes.
•The earliest involvement in the liver involves the
portal triads in the form of nodular aggregates of
lymphoid cells.
•Such involvement, if extensive, can spill into the
periportal area of the liver parenchyma.
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Clinical Correlation
•Clinical sequelae of hepatic involvement by lymphoma
can be none to extensive with the development of
symptoms of liver cell function compromise, including
jaundice, elevation of serum enzymes and coagulopathy.
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References
No suitable textbook reference
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| Lymphoma
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| Synopsis by: T.V.Rajan, M.D., Ph.D. (T56000M95906)[499]
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