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| Normal Stomach |
| Etiology • Not applicable. |
| Pathogenesis • Not applicable., |
| Epidemiology • Not applicable. |
| General Gross Description • Located in the left upper quadrant connecting esophagus and duodenum • Four zones including cardia (transition from esophagus), fundus or body, antrum and pylorus • Supplied by celiac axis, hepatic artery, and splenic artery |
| General Microscopic Description • Tall columnar epithelium covers surface with intervening pits (foveolae, crypts) • Glands emptying into pits vary with location in stomach • Cardiac and antral glands are mucin secreting with occasional parietal cells; glands and pits occupy approximately 1/2 the mucosal thickness • Fundic glands occupy 1/4 mucosal thickness, straight, and have abundant chief cells with basal nuclei and gray-blue cytoplasm as well as numerous parietal cells with deep pink cytoplasm • Lamina propria contains lymphocytes, fibroblasts and histiocytes; intraepithelial lymphocytes are rare; plasma cells are not considered normal • Muscularis mucosa above submucosa which lies on muscularis propria and serosa |
| Clinical Correlation • Not applicable. |
| References • Histology for Pathologists. Sternberg SS ed. New York: Raven Press, 1992. pp. 533-539. |
| Normal Stomach |
| Synopsis by: Melinda Sanders M.D. (T63000M00100)[543] |
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