|Squamous Metaplasia of Bladder|
•The etiology of squamous metaplasia is dependent upon the
underlying pathologic process, i.e, bladder calculi, extrophy of the
•Probably normal in women.
•The normal transitional epithelium will undergo squamous metaplasia as an adaptive change to chronic irritation, such as from bladder calculi.
•The epidemiology is dependent on the underlying disease
•Squamous metaplasia is found in a large percentage of women with no abnormalities.
•Squamous metaplasia may occur in situations of chronic irritation such as bladder calculi, extrophy of the bladder and schistosomiasis.
|General Gross Description|
•There is no striking gross changes to the epithelial
lining of the bladder.
•There may be a perception that the epithelial lining is paler and thicker than normal.
|General Micro Description|
•The normal transitional epithelium of the bladder is replaced by stratified squamous epithelium.
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 48