•Squamous metaplasia is usually an adaptive response of marginally viable epithelial cells adjacent to infarcts, which in turn may be secondary to massive prostatic enlargement.

•The marginally viable prostatic epithelial cells adjacent to an infarct will undergo squamous metaplasia to survive the circumstances of the local environment.

•The epidemiology is that of benign prostatic hyperplasia.

•Squamous metaplasia of the prostate can be seen adjacent to infarcts due to prostatic enlargement.

•The clinical picture will be that of benign prostatic hyperplasia.

•There are no specific gross features.

•Since this metaplastic change is a microscopic finding associated with benign prostatic hyperplasia (BPH), the gross feature will be that of BPH.

•The normal ductal and glandular epithelial cells of the prostate are transformed to squamous cells.

•The cells are no longer cuboidal or columnar but flattened.

•These cells may show keratinization and squamous pearl formation.

•Squamous metaplasia in the prostate can be seen adjacent to infarcts.

• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 48.

• Current literature from PubMed at National Library of Medicine