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| Seminoma |
| Etiology •Unknown. |
| Pathogenesis •Unknown. •Seminomas are germ cell neoplasms., |
| Epidemiology •Males. •Peak incidence in the fourth decade of life. |
| General Gross Description •On cut section, the tumor is usually gray-white, homogenous and lobular. •Necrosis and hemorrhage are inconspicuous in small tumors and more notable in larger tumors. |
| General Microscopic Description •Typical seminoma is composed of monotonous sheets of uniform round cells with rather clear cytoplasm and centrally located round nuclei with prominent nucleoli. •The stroma frequently shows lymphocytes, •Granulomatous inflammatory foci can be present. |
| Clinical Correlation •Unilateral non-painful testicular enlargement. •Seminoma occur most frequently in the fourth and fifth decade of life. |
| References • • Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1016-1017. |
| Seminoma |
| Synopsis by: Harold Yamase M.D. (T78000M90613)[237] |
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