| • The photograph shows the cut section of a
leiomyosarcoma removed from the region of the
bladder neck and prostate gland.
• The external contour is irregularly lobulated but
for the most part smooth. There are peripheral
regions however, showing necrosis and contour
irregularities.
• The viable central region is light tan and fairly homogenous. |
| Leiomyosarcoma of Prostate |
| Etiology |
•Unknown. |
| Pathogenesis |
•Unknown. |
| Epidemiology |
•Rare, however leiomyosarcomas are the most common sarcomas that involve the prostate gland in the adult. •Most patients are between 40 and 70 years old. |
| Clinical |
•Urinary obstruction. |
| General Gross Description |
•Median size of reported cases is 5 cm. •Cut surface is tan and fleshy. |
| General Micro Description |
•The tumor is a spindle cell neoplasm. •The greater the nuclear pleomorphism and the greater the number of mitotic figures, the more certain one is of malignancy. •Because smooth muscle tumors are rare in the prostate, criteria distinquishing leiomyosarcoma from leiomyoma have not been established. |
| Reference |
•Epstein JI. Prostate Biopsy Interpretation. New York: Raven Press, 1989. pp.223-224.
|
