| Leiomyosarcoma of Prostate
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Etiology
•Unknown.
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Pathogenesis
•Unknown.,
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Epidemiology
•Rare, however leiomyosarcomas are the most common sarcomas that involve the prostate gland in the adult.
•Most patients are between 40 and 70 years old.
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General Gross Description
•Median size of reported cases is 5 cm.
•Cut surface is tan and fleshy.
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General Microscopic Description
•The tumor is a spindle cell neoplasm.
•The greater the nuclear pleomorphism and the greater the number of mitotic figures, the more certain one is of malignancy.
•Because smooth muscle tumors are rare in the prostate, criteria distinquishing leiomyosarcoma from leiomyoma have not been established.
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Clinical Correlation
•Urinary obstruction.
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References
•Epstein JI. Prostate Biopsy Interpretation. New York: Raven Press, 1989. pp.223-224.
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| Leiomyosarcoma of Prostate
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| Synopsis by: Harold Yamase M.D. (T77100M88903)[474]
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