Squamous Cell Carcinoma in Situ (40X)

Squamous Cell Carcinoma in Situ (40X) • This close up image shows lack of maturation of the squamous epithelium. • The basal portion of the epithelium is to the lower right; the superficial epithelium is in the upper left hand corner. • The arrow points to a mitotic figure located only a few layers beneath the surface. • The location of this mitosis identifies the process as intraepithelial neoplasia or dysplasia. • Note the nuclei are round to oval with some chromatin clumping. (Description By:Melinda Sanders,M.D. ) (Image Contrib. by:Melinda Sanders,M.D. UCHC )