| The villi are relatively large in this immature placenta.
The intervillus space contains an excess number of nucleated cells for normal circulating maternal blood, as demonstrated by the black arrow. |
| Chronic Intervillositis ? |
| Etiology |
Unknown |
| Pathogenesis |
Unknonwn |
| Epidemiology |
May be associated with chronic non-specific villitis May be associated with euploid spontaneous abortion |
| Clinical |
May recur May be associated with decidual vascular thrombosis and euploid early spontaneous losses. |
| General Gross Description |
No gross findings |
| General Micro Description |
Accumulation of mononuclear cells (maternal CD3+ cells) in intervillous space May accompany actual villitis |
| Reference |
Benirschke K, Kaufmann P. Pathology of the human placenta, 3rd ed. New York: Springer-Verlag, 1995, pp. 596-620.
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