| • The blue arrows point to a typical "endometrial type" gland.
• The adjacent stroma contains spindly endometrial stroma.
• Together they resemble inactive endometrium. |
| Endometriosis |
| Etiology |
• unknown |
| Pathogenesis |
• hypotheses include
retrograde menstruation with implantation, metaplasia of
the pelvic peritoneum (Mullerian derivative) or
lymphovascular invasion |
| Epidemiology |
• reproductive age women esp 4th
and 5th decade • often associated with infertility without evidence
of actual tubal obstruction |
| Clinical |
• may be asymptomatic or experience severe pelvic pain with
menstruation, dyspareunia, dysuria, or pain on defecation • therapy is dependent on symptoms and whether or not there is a desire to maintain fertility |
| General Gross Description |
• cortical surface may be dull with adhesions • cysts contain old brown blood "chocolate" • generally unilocular • granular, shaggy brown lining • also affects pelvic and uterine ligaments, cul-de-sac,
peritoneum, abdominal scars and occasionally distant sites |
| General Micro Description |
•
endometrial glands and/or • endometrial stroma and/or • hemosiderin laden macrophages • usually abundant scar |
| Reference |
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1054-1055
|