Teratoma
Teratoma

•  The red arrows point to the perimeter of a nest of immature cartilage.

•  The nuclei are spindly and not located within identifiable lacunae.

•  The stroma is white, lacking the bluish coloration of mature cartilage.


(Image Contrib. by:UCHC)(Description by: Melinda Sanders, M.D.)
T87000M90803
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Immature (Malignant) Teratoma
Etiology

• unknown


Pathogenesis

• proliferation of a meiotic germ cell


Epidemiology

• rare neoplasm


Clinical

• women with an average age of 18 who present with abdominal pain and enlargement

• grow rapidly and spread

• treat locally with surgery and may add chemotherapy if disease has spread

•For more information on prognosis and treatment, consult the NCI web site.

Visit National Cancer Institute for Current Treatment


General Gross Description

• smooth external surface

• predominantly solid although may be cystic

• necrosis and hemorrhage

• hair, keratinaceous debris, bone and cartilage


General Micro Description

• IMMATURE (FETAL) tissues from all three germ cell layers

• immature neural elements are common and may correlate with outcome


Reference

• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. pp. 1073


• Current literature from PubMed at National Library of Medicine


Synopsis by: Melinda Sanders M.D., UCHC
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