| Immature (Malignant) Teratoma
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Etiology
•
unknown
|
Pathogenesis
• proliferation of a meiotic germ cell,
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Epidemiology
• rare neoplasm
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General Gross Description
• smooth external
surface
• predominantly solid although may be cystic
• necrosis and hemorrhage
• hair, keratinaceous debris, bone and
cartilage
|
General Microscopic Description
• IMMATURE (FETAL) tissues from all three germ cell
layers
• immature neural elements are common and may correlate
with outcome
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Clinical Correlation
• women under 21 with abdominal pain and enlargement
• Stage I confined to the ovary, II confined to the pelvis,
III confined to peritoneal cavity, IV distant metastases
• treat Stage I with surgery and chemotherapy as warranted
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References
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. pp. 1073
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| Immature (Malignant) Teratoma
|
| Synopsis by: Melinda Sanders M.D. (T87000M90803)[48]
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