| The red arrows point to the perimeter of a nest of immature cartilage.
The nuclei are spindly and not located within identifiable lacunae.
The stroma is white, lacking the bluish coloration of mature cartilage. |
| Immature (Malignant) Teratoma |
| Etiology |
unknown |
| Pathogenesis |
proliferation of a meiotic germ cell |
| Epidemiology |
rare neoplasm |
| Clinical |
women with an average age of 18 who present with abdominal pain and enlargement grow rapidly and spread
treat locally with surgery and may add chemotherapy if disease has spread
For more information on prognosis and treatment, consult the NCI web site. |
| General Gross Description |
smooth external
surface predominantly solid although may be cystic necrosis and hemorrhage hair, keratinaceous debris, bone and
cartilage |
| General Micro Description |
IMMATURE (FETAL) tissues from all three germ cell
layers immature neural elements are common and may correlate
with outcome |
| Reference |
Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. pp. 1073
|