| • The polyp contains multiple dilated endometrial glands
• Some contain inspissated secretions.
• The stroma is relatively fibrous and eosinophilic. |
| • The polyp contains multiple dilated endometrial glands
• Some contain inspissated secretions.
• The stroma is relatively fibrous and eosinophilic. |
| Polyp |
| Etiology |
•unknown, some association with
tamoxifen a systemic
anti-estrogen with mixed effects on the uterus •may be associated with increased unopposed estrogen |
| Pathogenesis |
•unknown •• local hyperresponsiveness to estrogen with failure to
respond to progesterone |
| Epidemiology |
•perimenopausal women |
| Clinical |
•irregular menses or
asymptomatic •treatment with removal is generally curative |
| General Gross Description |
•sessile or pedunculated soft tan masses •0.5 cm to 3.0 cm in diameter, usually •may protrude through cervical os |
| General Micro Description |
•glands varying from proliferative to hyperplastic mixed
with glands showing cystic dilatation with secretion •dense fibrous stroma •collarette of blood vessels with fibrotic walls •occasionally glands may be atrophic |
| Reference |
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1059
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