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Normal Membranes (10X)
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Normal Membranes (10X)

The arrow points to the amniotic epithelium which is relatively columnar in this late term placenta.
The blue arrows point to the cells of the chorion which are extravillus trophoblast.
(Description By:Linda Ernst )
(Image Contrib. by:Linda Ernst UCHC )
Normal Membranes
Etiology

Not applicable
Pathogenesis

Not applicable,
Epidemiology

Not applicable
General Gross Description

Normally translucent gray and shiny
General Microscopic Description

Layer of amnionic epithelium with associated connective tissue termed mesoderm; derived from fetal ectoderm
Separates readily (since it is held there by pressure of amniotic fluid) from underlying chorionic mesoderm which includes residual extravillous trophoblast, avascularized atretic villous remnants (chorion laeve) and decidualized endometrial stromal cells
Maternal vessels (unoconverted spiral arteries) provide blood flow
Formation of membranes occurs between 3rd week post conception and 16 week
Clinical Correlation

Not applicable
References

Benirschke K, Kaufmann P. Pathology of the human placenta, 3rd ed. New York: Springer-Verlag, 1995, pp. 268-271.
Normal Membranes
Synopsis by: Melinda Sanders M.D. (T88200M00100)[428]
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