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Fetal membranes (4X)
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Fetal membranes (4X)

This is a photo of fetal membranes.
Black arrow indicates the simple squamous to cuboidal amniontic epithelium. Note the layer of amniotic connective tissue beneath the epithelium.
There is artifactual separation of the amnion and chorion.
Blue arrow points to the trophoblast cells of the chorion which form a continuous layer. The connective tissue of the chorion is the thin layer just above the trophoblasts.
(Description By:Melinda Sanders, M.D. )
(Image Contrib. by: UCHC )
Normal Membranes
Etiology

Not applicable
Pathogenesis

Not applicable,
Epidemiology

Not applicable
General Gross Description

Normally translucent gray and shiny
General Microscopic Description

Layer of amnionic epithelium with associated connective tissue termed mesoderm; derived from fetal ectoderm
Separates readily (since it is held there by pressure of amniotic fluid) from underlying chorionic mesoderm which includes residual extravillous trophoblast, avascularized atretic villous remnants (chorion laeve) and decidualized endometrial stromal cells
Maternal vessels (unoconverted spiral arteries) provide blood flow
Formation of membranes occurs between 3rd week post conception and 16 week
Clinical Correlation

Not applicable
References

Benirschke K, Kaufmann P. Pathology of the human placenta, 3rd ed. New York: Springer-Verlag, 1995, pp. 268-271.
Normal Membranes
Synopsis by: Melinda Sanders M.D. (T88200M00100)[428]
Search Medline at National Library of Medicine
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