Malignant Lymphoma - high grade small non-cleaved cell type (Burkitts)
Malignant Lymphoma - high grade small non-cleaved cell type (Burkitts)

The characteristic feature of this lymphoma is clearly seen in this low power view.
One can see that there appear to be two cell types in this field, a small cell which is deeply staining and densely packed.
Interspersed among these cells are large cells which appear to occupy an empty space.
This gives rise to the characteristic "starry sky" appearance.
The small cells are the proliferating malignant cells; the larger cells that appear to be within lacunae are benign tissue macrophages that are reacting to the lymphoma.
(Description By:T.V.Rajan, M.D. )
(Image Contrib. by:T.V.Rajan, M.D. UCHC )