Hodgkins Disease - lymphocyte predominant
Hodgkins Disease - lymphocyte predominant

A medium power view of a lymphocyte predominant Hodgkins disease shows the two characteristic features of this disease.
Towards the center of this image is a large cell with abundant cytoplasm and two nuclei.
Notice that these two nuclei have a vesicular chromatin pattern, with a dark staining rim of chromatin and a large paler interior.
The two large, deep staining structures at the centers of these two nuclei are the nucleoli.
Almost every other cell in this field is a small lymphocyte.
To the right of the Reed-Sternberg cell at the center of this image is a lymphocyte that appears to be undergoing mitotic division.
(Description By:T.V.Rajan, M.D. )
(Image Contrib. by:T.V.Rajan, M.D. UCHC )