Hodgkins Disease - mixed cellularity
Hodgkins Disease - mixed cellularity

Towards the left bottom of this image, is the cell that is diagnostic of a Hodgkins lymphoma, namely the Reed-Sternberg cell.
This cell is a large cell with abundant cytoplasm and at least two nuclei with prominent nucleoli.
These features are also filled by the cell towards the left bottom of this image.
The rest of the image shows the typical feature of a mixed cellularity Hodgkins, namely the multiplicity of cell types and the lack of organization in the form cortex and medulla and germinal centers.
(Description By:T.V.Rajan, M.D. )
(Image Contrib. by:T.V.Rajan, M.D. UCHC )