Hodgkins Disease - lymphocyte depletion

Hodgkins Disease - lymphocyte depletion •A medium power view of a lymphocyte depleted Hodgkins disease. •Notice the numerous large cells that are distributed over the entire field. •A higher power view will demonstrate that many of these are the characteristic Reed-Sternberg cells. •The most noticeable thing about this field, is the relatively sparse cellularity of this tumor. •This lack of cells is typical of the lymphocyte depletion type Hodgkins disease. (Description By:T.V.Rajan, M.D. ) (Image Contrib. by:T.V.Rajan, M.D. UCHC )