Hodgkins Disease - lymphocyte depletion

Hodgkins Disease - lymphocyte depletion •A high power view of a lymphocyte depleted Hodgkins disease. •Numerous characteristic Reed-Sternberg cells are seen in this field. •In between these cells, the most prominent feature is the presence of bundles of collagen that appear to make up most of the tissue. •A sparse number of lymphocytes and other cell types are also seen. •Lymphocyte depleted Hodgkins disease is characterized by abundant Reed-Sternberg cells, formation of collagen bundles, and relative lack of cells between the proliferating Reed-Sternberg cells. (Description By:T.V.Rajan, M.D. ) (Image Contrib. by:T.V.Rajan, M.D. UCHC )