• This angiofibroma has been bivalved and the external view of both sides is demonstrated.
• The neoplasm has a smooth surface which is yellow tan.
• The areas of black discoloration represent hemorrhage.
• They are likely to be the sources of epistaxis (nosebleed) that was a presenting symptom.
• Increases in size under the influence of testosterone
• Predilection for teenage boys (peak incidence at age 15)
• Rarely ever seen in girls, if at all
• Present with nasal obstruction and bleeding, as arise from lateral nasopharynx
• May bleed profusely with surgery, which is treatment of choice
• May need chemotherapy if surgery cannot remove intracranial extension
|General Gross Description|
• Firm, fibrous masses
• Well circumscribed
|General Micro Description|
• Numerous vascular spaces embedded in stroma which is collagenized
• Spaces generally lined by single layer of endothelium
• Sternberg SS ed. Diagnostic Surgical Pathology, 2d edition, Lippincott-Raven; Philadelphia. 1996, pp. 874-5.