| • This angiofibroma has been bivalved and the external view of both sides is demonstrated.
• The neoplasm has a smooth surface which is yellow tan.
• The areas of black discoloration represent hemorrhage.
• They are likely to be the sources of epistaxis (nosebleed) that was a presenting symptom. |
| Angiofibroma |
| Etiology |
• Unknown • Increases in size under the influence of testosterone |
| Pathogenesis |
• Unknown |
| Epidemiology |
• Predilection for teenage boys (peak incidence at age 15) • Rarely ever seen in girls, if at all |
| Clinical |
• Present with nasal obstruction and bleeding, as arise from lateral nasopharynx • May bleed profusely with surgery, which is treatment of choice • May need chemotherapy if surgery cannot remove intracranial extension |
| General Gross Description |
• Firm, fibrous masses • Well circumscribed |
| General Micro Description |
• Numerous vascular spaces embedded in stroma which is collagenized • Spaces generally lined by single layer of endothelium |
| Reference |
• Sternberg SS ed. Diagnostic Surgical Pathology, 2d edition, Lippincott-Raven; Philadelphia. 1996, pp. 874-5.
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