| Normal
|
Etiology
• Not
applicable
|
Pathogenesis
• Not applicable,
|
Epidemiology
• Not applicable
|
General Gross Description
• Weight 250-350 grams each
• Soft, well aerated (crepitant), pink tan
• Often tracing of black carbon pigment in macrophages outlining the subpleural
lymphatics
|
General Microscopic Description
• Bronchi, containing cartilage in their walls, branch to form
bronchioles, lacking cartilage, ending in terminal bronchioles which give
rise to respiratory bronchioles and then alveoli
• Clara cells increase and goblet cells decrease progressing down the
bronchial divisions.
• Other cells include Kulchitsky (neuroendocrine cells) and ciliated
columnar cells
• Alveolar membrane includes type 1 pneumocytes, alveolar basement membrane,
capillary basement membrane, and endothelial cells.
|
Clinical Correlation
• Not applicable
|
References
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp. 673-674
|
| Normal
|
| Synopsis by: Melinda Sanders M.D. (T28000M00100)[124]
|
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