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Lung with Aspiration of Gastric Contents
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Lung with Aspiration of Gastric Contents

The bronchial mucosa is a vivid red due to irritation from aspiration of gastric contents.
Adjacent pulmonary parenchyma is also deeply congested.
(Description By:Melinda Sanders, M.D. )
(Image Contrib. by: UCHC )
Aspiration Pneumonia
Etiology

Aspiration of gastric contents
Pathogenesis

Gastric acid causes chemical bronchitis
Infection with aspirated organisms frequent.,
Epidemiology

Complicates coma, anesthesia.
Patients with prolonged vomiting
Patients with depressed gag reflex
General Gross Description

Intensely congested bronchial mucosa, which may ulcerate
Particles of food may be grossly visible in the bronchi
Patchy bronchopneumonia may develop in the adjacent parenchyma
General Microscopic Description

Acute inflammation in the bronchial lumen
Acute inflammation of the bronchial wall
Marked acute congestion
Food particles may be visible microscopically
Neutrophils in the alveoli adjacent to terminal bronchioles
May develop into bronchopneumonia
Clinical Correlation

Leads to bronchopneumonia
Complete recovery usual with appropriate management.
References

Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp. 694-698.
Aspiration Pneumonia
Synopsis by: Melinda Sanders M.D. (T26000M79000)[127]
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