Normal
Normal

•  External surface of a normal right lung.

•  Initials identify upper (U), middle (M), and lower (L) lobes.

•  Carbon pigment trapped in subpleural lymphatics creates the lines of black on the external surface (arrows).


(Image Contrib. by:Saint Francis Hospital)(Description by: Melinda Sanders, M.D.)
T28000M80703
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Normal
Etiology

• Not applicable


Pathogenesis

• Not applicable


Epidemiology

• Not applicable


Clinical

• Not applicable


General Gross Description

• Weight 250-350 grams each

• Soft, well aerated (crepitant), pink tan

• Often tracing of black carbon pigment in macrophages outlining the subpleural lymphatics


General Micro Description

• Bronchi, containing cartilage in their walls, branch to form bronchioles, lacking cartilage, ending in terminal bronchioles which give rise to respiratory bronchioles and then alveoli

• Clara cells increase and goblet cells decrease progressing down the bronchial divisions.

• Other cells include Kulchitsky (neuroendocrine cells) and ciliated columnar cells

• Alveolar membrane includes type 1 pneumocytes, alveolar basement membrane, capillary basement membrane, and endothelial cells.


Reference

• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp. 673-674


• Current literature from PubMed at National Library of Medicine


Synopsis by: Melinda Sanders M.D., UCHC
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