| • External surface of a normal right lung.
• Initials identify upper (U), middle (M), and lower
(L) lobes.
• Carbon pigment trapped in subpleural lymphatics creates the lines of black on the external surface (arrows). |
| Normal |
| Etiology |
• Not
applicable |
| Pathogenesis |
• Not applicable |
| Epidemiology |
• Not applicable |
| Clinical |
• Not applicable |
| General Gross Description |
• Weight 250-350 grams each • Soft, well aerated (crepitant), pink tan • Often tracing of black carbon pigment in macrophages outlining the subpleural
lymphatics |
| General Micro Description |
• Bronchi, containing cartilage in their walls, branch to form
bronchioles, lacking cartilage, ending in terminal bronchioles which give
rise to respiratory bronchioles and then alveoli • Clara cells increase and goblet cells decrease progressing down the
bronchial divisions. • Other cells include Kulchitsky (neuroendocrine cells) and ciliated
columnar cells • Alveolar membrane includes type 1 pneumocytes, alveolar basement membrane,
capillary basement membrane, and endothelial cells. |
| Reference |
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp. 673-674
|