| Burn
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Etiology
•Burns can occur due to a variety of reasons, including
exposure to fire or fluids at high temperature,
chemicals such as acids, bases and oxidizing agents, high
voltage electricity and exposure to the sun.
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Pathogenesis
•Burns cause coagulation necrosis of exposed tissues.,
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Epidemiology
•Common
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General Gross Description
•Burns are classified as partial or full thickness
depending upon the depth to which the skin has been
subjected to injury.
•In partial thickness wounds, only the superficial layers
of the epidermis are subjected to injury.
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General Microscopic Description
•Cells show evidence of coagulation necrosis and are
converted into a uniform pink staining material.
•In full thickness burns, the entire epidermis, parts or
all of the dermis, and the subcutaneous tissue may be
injured.
•As with a particular thickness burn, the tissue
involved is converted into a homogenously staining
material.
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Clinical Correlation
•The prognosis for burns is always guarded, especially
if they involve >50% of the body surface.
•Healing depends on the depth of the burn.
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References
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp. 399.
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• Pathology, 2nd edition: Rubin E, Farber JL (eds). Philadelphia, J.B. Lippincott, 1994, pp. 316.
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| Burn
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| Synopsis by: T.V.Rajan, M.D., Ph.D. (T01000M11100)[516]
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